1890 Coca and its Therapeutic Application by Angelo Mariani

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ing manner;"The exciting cerebro-medullary action of these principles causes an increase of the intellectual and physical activity, at the same time that the analgesic action on the extremities of the sensitive and sensory nerves, prevents the pangs of hunger, and consequently the accompanying moral and physical depression." From another point of view, M.Laffont adds,that the dynamogenic action of the active principles of Coca on the smooth-fibered muscles"indicates its use in the list of atonic gastro-intestinal diseases, flatulent dyspepsia, dila tation of the stomach, paresis of the intestines, of the bladder, etc." It is impossible for us to recount here all the trials which have been made with Cocaine; we will only quote the names of Dr. Deneffe, Dr. Charpentier, Dr. Morell Mac kenzie, Dr. Lennox Browne, Dr. Sajous, Dr. J. Leonard Corning, Dr.Beverly Robinson,Dr. Louis Elsberg,Dr.W. Oliver Moore, Dr. Vincenzo Cozzolino, Dr. Abadie, Dr. Galezowski, Dr. Meyer, Dr. de Wecker, Dr. Doleris, Dr. David Colombe,Dr. Rigolet, and Dr. Brasseur, the major ity of whom have studied this que.stion from an ocular, therapeutical, obstetrical, dental,and laryngological point of view.