1890 Coca and its Therapeutic Application by Angelo Mariani

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borne by the most delicate stomachs; hence it becomes a valuable adjuvant in the treatment of the endemic dysen teries and diarrhoeas of tropical countries. "-Finally,its exclusive use, even its excessive use for several days, has not seemed to us to exert any injuri ous influence on the system,as the abuse of coffee or of alcoholic drinks had certainly done under like circum stances." Dr. Fordyce Barker, Dr. J. H. Douglas, Dr. Henry B. Sands and Dr.Geo.F.Shrady have authorized us to make known that it was due to TM Mariani, added to milk (in the proportion of a teaspoonful of the TM to a cup of milk), that they were able to nourish Gen.Grant,the ex- President, when he wasunable to support any other food. By this means they succeeded in prolonging the life of their illustrious patient for several months. Coca taken in infusion gave excellent results to Tschudy while he was sojourning in the valley of the Puna, the highest in Bolivia,which has given its name to the disease of mountain sickness,known in Peru by the name Maide Puna,also designated by the words sorroche,veta and mareo; this last term shows clearly enough the analogy which exists between sea-sickness and the influence of great alti tudes on the human body. Experience has proved the usefulness of Coca against dyspnoea and vomiting, so that the Indians who make ascensions always carry a stock of Coca with them. Dr.Tschudy found himself comfortable by the use of it while hunting in those valleys, at a height of ten to twelve thousand feet above the sea. Dr.Salemi,of Nice, gives an account of a case of epi lepsy in a woman,38 years of age,cured by the daily and prolonged use of TM Mariani, given in increasing doses (ten drops daily at first and eighty drops daily.at the end of a month). This case is not an isolated one.